Who Done It? Rurality vs. SES as Critical Factors in Evaluating the Prevalence of Child Psychosocial Concerns in Primary Care

The purpose of this study was to evaluate the prevalence of child psychosocial concerns in rural primary care, hypothesized to be greater than national averages due to lacking mental health services in rural areas. This study was an examination of the role of SES, various definitions of “rural,” and the interaction of SES and rurality, in predicting parent-reported child psychosocial concerns in Appalachian primary care clinics. Caregivers presenting with their child at one of 8 pediatric primary care sites (n=2,672) were recruited to complete a measure assessing demographics and the Pediatric Symptom Checklist (PSC). Results showed that while rural status was not associated with PSC scores, higher parental education was associated with lower rates of clinically significant psychosocial concerns. The present study failed to replicate prior preliminary findings that child psychosocial concerns are more prevalent in rural primary care. SES, rather than rurality, appeared to be the primary predictor of such concerns

Using the Theory of Planned Behavior to Predict Executives’ Intentions to Hire Psychologists in Federally Qualified Health Centers

Health psychologists with training in integrated care are ideal candidates to work in Federally Qualified Health Centers (FQHCs). However, despite the large documented need for more behavioral health providers in FQHCs, psychologists are underrepresented in this setting compared to other behavioral health professions. The purpose of this study was to: 1) examine the specific beliefs that are most relevant to executives’ intentions to hire psychologists, 2) determine how executives’ perceived control over hiring psychologists varies by several demographic variables, and 3) examine how well the Theory of Planned Behavior (TPB) predicts executives’ intentions to hire psychologists. Method: Executives (N = 222) from every US Census defined division of the country completed an online TBP survey assessing demographics and beliefs about hiring psychologists. Path analysis was used to examine the relationships between TPB variables. Results: Executives ranked psychologists as highly proficient in integrated care and general clinical skills but less proficient in research and leadership skills. Compared to other skills, executives ranked research skills as lower in importance for clinical staff to possess. Longer executive job tenures (but not FQHC budget or rural status) predicted more perceived control over hiring practices. The standard TPB was a poor fit with the data, but a modified version explained 78% of the variance in executives’ intent to hire psychologists. In this model, executives’ normative beliefs were most predictive of their intent to hire. Implications: Results point to the importance of internal champions within FQHCs who advocate for psychologists as well as the need for early interprofessional education. Opportunities exist for health service psychologists to promote the value of research to executives and to differentiate themselves by emphasizing their skills in research and implementation science

The Perfect Storm: Examining User Experience and Conducting a Usability Test to Investigate a Disruptive Academic Library Web Site Redevelopment

The researchers conducted a task-based usability test of the effectiveness of online research beginning on the library Web site homepage. The participants included five university faculty members, six graduate students, and six undergraduate students. All participants reported feeling satisfied with their overall research experience, though most were unable to effectively complete all the research tasks of the test. The researchers identified weaknesses in the approach and process of many participants, and overall usability issues of the library discovery tool and other library Web site pages and research interfaces. Findings indicate the need to strategically incorporate self-service information literacy and research skills help into the library Web site, and to implement navigation and design changes to the library homepage, discovery tool interface, online catalog, and across all the library\u27s Web services

Champion Teams as a Mechanism for Developing Team Care Capacity

Practice transformation toward team care as a singular undertaking can be daunting. In this presentation, we describe the development of a mechanism for small, iterative and sustainable practice changes toward team care known as Champion Teams. Champion Teams are based on the Institute of Medicine\u27s learning health care system approach in which practitioners develop an internal mechanism for and culture around digesting and implementing new evidence based practices on an ongoing basis. In addition to presenting the Champion Team concept as a strategy for implementing new team care initiatives, interprofessional providers will present two case examples from each adult and pediatric primary care. At the conclusion of this presentation, participants will be able to: Define the term learning healthcare system and its application to Champion Teams. Describe the utility of and keys to implementing Champion Teams. Describe two examples of Champion Teams and the application of this mechanism to making data-informed changes toward team-based care in their own setting

Delivery of Nucleic Acids and Nanomaterials by Cell-Penetrating Peptides: Opportunities and Challenges

Many viral and nonviral systems have been developed to aid delivery of biologically active molecules into cells. Among these, cell-penetrating peptides (CPPs) have received increasing attention in the past two decades for biomedical applications. In this review, we focus on opportunities and challenges associated with CPP delivery of nucleic acids and nanomaterials. We first describe the nature of versatile CPPs and their interactions with various types of cargoes. We then discuss in vivo and in vitro delivery of nucleic acids and nanomaterials by CPPs. Studies on the mechanisms of cellular entry and limitations in the methods used are detailed

Advanced sensors technology survey

This project assesses the state-of-the-art in advanced or 'smart' sensors technology for NASA Life Sciences research applications with an emphasis on those sensors with potential applications on the space station freedom (SSF). The objectives are: (1) to conduct literature reviews on relevant advanced sensor technology; (2) to interview various scientists and engineers in industry, academia, and government who are knowledgeable on this topic; (3) to provide viewpoints and opinions regarding the potential applications of this technology on the SSF; and (4) to provide summary charts of relevant technologies and centers where these technologies are being developed

Collaboration Between Health Sciences Librarians and Faculty as Reflected by Articles Published in the Journal of the Medical Library Association

A recent study by Higgins and colleagues reports that the Journal of the Medical Library Association (JMLA) had the highest percentage of articles with both librarian and faculty co-authors out of 13 peer-reviewed journals in STEM librarianship and education between 2005 and 2014. A deeper and updated analysis of JMLA research articles and case studies published between 2008 and 2017 revealed that 29% of articles had both librarian and faculty co-authors. The main topics of librarian-faculty collaboration as described in these articles were related to patient and consumer health information and clinical information-seeking and decision-making by healthcare providers. Most faculty co-authors came from the disciplines of biomedical/health informatics and biostatistics and library and information science. The publication of these articles in JMLA provides evidence of health sciences librarians and information specialists’ ability to collaborate with faculty members to advance the knowledgebase and practice of librarianship and the health sciences

Genetic Dissection of Acute Ethanol Responsive Gene Networks in Prefrontal Cortex: Functional and Mechanistic Implications

Background Individual differences in initial sensitivity to ethanol are strongly related to the heritable risk of alcoholism in humans. To elucidate key molecular networks that modulate ethanol sensitivity we performed the first systems genetics analysis of ethanol-responsive gene expression in brain regions of the mesocorticolimbic reward circuit (prefrontal cortex, nucleus accumbens, and ventral midbrain) across a highly diverse family of 27 isogenic mouse strains (BXD panel) before and after treatment with ethanol. Results Acute ethanol altered the expression of ~2,750 genes in one or more regions and 400 transcripts were jointly modulated in all three. Ethanol-responsive gene networks were extracted with a powerful graph theoretical method that efficiently summarized ethanol\u27s effects. These networks correlated with acute behavioral responses to ethanol and other drugs of abuse. As predicted, networks were heavily populated by genes controlling synaptic transmission and neuroplasticity. Several of the most densely interconnected network hubs, including Kcnma1 and Gsk3β, are known to influence behavioral or physiological responses to ethanol, validating our overall approach. Other major hub genes like Grm3, Pten and Nrg3 represent novel targets of ethanol effects. Networks were under strong genetic control by variants that we mapped to a small number of chromosomal loci. Using a novel combination of genetic, bioinformatic and network-based approaches, we identified high priority cis-regulatory candidate genes, including Scn1b,Gria1, Sncb and Nell2. Conclusions The ethanol-responsive gene networks identified here represent a previously uncharacterized intermediate phenotype between DNA variation and ethanol sensitivity in mice. Networks involved in synaptic transmission were strongly regulated by ethanol and could contribute to behavioral plasticity seen with chronic ethanol. Our novel finding that hub genes and a small number of loci exert major influence over the ethanol response of gene networks could have important implications for future studies regarding the mechanisms and treatment of alcohol use disorders

Assessing and Treating ADHD in Integrated Primary Care Setting

Book Summary: This book is really a reflection of the past more than 20 years of work with teens and suicide prevention in the state of Kentucky. The work to establish the “Stop Youth Suicide Campaign (SYS)” has resulted in contact with many young adults, and we have found that the most important thing for all of them was finding a caring person they trust and can talk to. Because of the constant need, the SYS went from a goal of being a one year awareness campaign to becoming a major community resource, working with the state and local governments and state legislators to add as many resources as possible. We have witnessed for the first time a drop of youth suicide rates below the national average, according to the 2013 Youth Risk Behavior Surveillance done biannually by the Center for Disease Control. In this book, we will tackle various topics and specific populations in relation to suicide written by people who work with teens and care about them